Ensuring nuclear safety has been an ongoing and significant concern worldwide. Although the Fukushima Daiichi nuclear power plant accident has undermined public confidence in its safety, many of Asia's emerging economies still have plans to introduce nuclear energy. This paper analyzes the possible development of nuclear energy in Asia's emerging economies and considers the implications for nuclear safety. The analysis reveals that insufficient financial, technical, and institutional capacities could be complemented by external support and assistance and that public acceptance is vital for launching nuclear power programs. While Asia's emerging economies expect regional or international cooperation and assistance from potential supplier countries, the regional cooperation framework for nuclear safety is underdeveloped and Asian supplier countries have insufficient capabilities, particularly in legal and regulatory aspects. An effective regional cooperation mechanism needs to be established to ensure nuclear safety, which requires immediate action from Japan.